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A Randomized Controlled Trial Of the Effectiveness of Planning Strategies in the Adherence to Medication for Coronary Artery Disease


Lourenço LBA, Rodrigues RCM, Ciol MA, São-João TM, Cornélio ME, Dantas RAS, Gallani M-C



Publication Info:

Journal of Advanced Nursing, 70(7):1616-1628


AIM: To examine the effect of action and coping planning strategies in the adherence to medication among outpatients with coronary artery disease.
BACKGROUND: Action and coping planning strategies are based on implementation intention, which requires self-regulation by the individual, to prioritize intentionally planned responses over learned or habitual ones, from daily routines to stressful situations.
DESIGN: Randomized controlled trial.
METHODS: Participants (n = 115) were randomized into intervention (use of action and coping planning strategies, n = 59) or control (usual care, n = 56) groups. The study was conducted between June 2010-May 2011 in two in-person visits: baseline and 2-month follow-up. Participants in the intervention group received telephone reinforcement between baseline and 2-month follow-up. Adherence to medication for cardioprotection and symptoms relief was evaluated by proportion of adherence, global measure of adherence evaluation and Morisky Self-Reported Measure of Medication Adherence Scale at both baseline and 2-month follow-up.
FINDINGS: When using the measure of global measure of adherence, participants in the intervention group reported adherence to therapy more often than controls (odds ratio = 5.3), but no statistically significant change was observed in the other two outcome measures.
CONCLUSION: This study has shown that individuals who use action and coping planning report higher adherence to drug treatment, when measured by the global adherence evaluation. Further studies with longer follow-ups are needed to assess if the effect of planning strategies has long-term duration.
Epub ahead of print doi: 10.1111/jan.12323

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